nonlinear regression analysis of the saturation equation graphpad prism 5 (GraphPad Software Inc)
Structured Review

Nonlinear Regression Analysis Of The Saturation Equation Graphpad Prism 5, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nonlinear regression analysis of the saturation equation graphpad prism 5/product/GraphPad Software Inc
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "Metabolism of bupropion by baboon hepatic and placental microsomes"
Article Title: Metabolism of bupropion by baboon hepatic and placental microsomes
Journal: Biochemical pharmacology
doi: 10.1016/j.bcp.2011.04.014
Figure Legend Snippet: A representative saturation curve of OH-BUP formation by baboon hepatic microsomes. The rate of bupropion hydroxylation to OH-BUP was dependent on bupropion concentration and exhibited typical saturation kinetics.
Techniques Used: Concentration Assay
Figure Legend Snippet: The representative saturation curve of threohydrobupropion formation by baboon placental microsomes (A) and the effect of chemical inhibitors selective to carbonyl reductases on the formation of threo- and erythrohydrobupropion by baboon placental microsomes (B). The inhibitors of carbonyl reductase are: 4-methylpyrazole (4-MP, 500µM), barbital (BAR, 500µM), flufenamic acid (FLU, 5µM), dicumarol (DIC, 500µM), menadione (MEN, 100µM), and 18β-glycyrrhetinic acid (18β-GA, 0.1µM). The rates of threo-(TB) and erythrohydrobupropion (EB) are expressed as percent of control (absence of inhibitor) and represent the mean ± S.D. of triplicate experiments. ** Statistical significance of p < 0.01 as determined by one-way ANOVA with Tukey’s comparison.
Techniques Used: Control, Comparison